Title | Year | Role | Notes |
|---|---|---|---|
| Vita coi figli (Life With the Sons) | 1990 | Elda | |
| Briganti – Amore e libertà (Bandits – Love and Liberty) | 1990 | Costanza | |
| la riffa | 1991 | Francesca | |
| Bram Stoker's Dracula | 1992 | One of Dracula's brides | |
| ostinato destino | 1992 | Marina/ Angela | |
| I Mitici | 1994 | Deborah | |
| Pala di Neve | 1995 | Melina | |
| Il cielo é sempre piú blu | 1995 | ||
| Joseph | 1995 | Pharaoh's wife | |
| L'Appartement | 1996 | Lisa | Nominated—César Award for Best Supporting Actress |
| Sorellina e il principe del sogno (uncredited) | 1996 | Princess | |
| Stressati | 1997 | ||
| Dobermann | 1997 | Nat the Gypsy | |
| Mauvais genre | 1997 | Camille | |
| Come mi vuoi | 1997 | Nellina | |
| Le plaisir | 1998 | Girl | |
| Compromis | 1998 | Monique | |
| Ultimo capodanno dell'umanità | 1998 | Giulia Giovannini | |
| A los que aman | 1998 | Valeria | |
| Comme un poisson hors de l'eau | 1999 | Myrtille | |
| Mediterranées | 1999 | Marguerite | |
| Under Suspicion | 2000 | Chantal Hearst | |
| Franck Spadone | 2000 | Laura | |
| Malèna | 2000 | Malèna Scordia | |
| Brotherhood of the Wolf | 2001 | Sylvia | |
| Astérix & Obélix: Mission Cléopâtre | 2002 | Cleopatra | |
| Irréversible | 2002 | Alex | |
| Remember Me, My Love | 2003 | Alessia | Nastro d'Argento award for Best Supporting Actress |
| Tears of the Sun | 2003 | Lena Fiore Kendricks | |
| The Matrix Reloaded | 2003 | Persephone | |
| Enter the Matrix (video game) | 2003 | Persephone | |
| The Matrix Revolutions | 2003 | Persephone | |
| The Passion of the Christ | 2004 | Mary Magdalene | |
| Secret Agents | 2004 | Barbara / Lisa | |
| She Hate Me | 2004 | Simona Bonasera | |
| The Brothers Grimm | 2005 | The Mirror Queen | |
| How Much Do You Love Me? | 2005 | Daniela | |
| Sheitan | 2006 | La belle vampiresse | |
| N (Io e Napoleone) | 2006 | Baronessa Emilia Speziali | |
| The Stone Council | 2006 | Laura Siprien | |
| Heartango (short film for Intimissimi) | 2007 | L'inafferrabile/ La passionale / L'indecisa / La curiosa / L'aggressiva / La mamma / La premurosa | |
| Manuale d'amore 2 (Capitoli successivi) | 2007 | Lucia | |
| Shoot 'Em Up | 2007 | Donna Quintano | |
| Le deuxième souffle | 2007 | Manouche | |
| Sanguepazzo | 2008 | Luisa Ferida | |
| L'uomo che ama | 2008 | Alba | |
| Don't Look Back | 2009 | Jeanne | |
| The Private Lives of Pippa Lee | 2009 | Gigi Lee | |
| Baarìa – La porta del vento | 2009 | Bricklayer's girlfriend | |
| Omaggio a Roma | 2009 | Tosca | |
| The Whistleblower | 2010 | Laura Levin | |
| The Sorcerer's Apprentice | 2010 | Veronica | |
| Rose, c'est Paris | 2010 | L'esprit de gala | |
| Manual of Love 3 | 2011 | Viola | |
| Guardian of the Harem | 2011 | ||
| That Summer | 2011 |
